Nicotine Salts are the natural state of nicotine found in tobacco leaves. In an e-liquid, they're shown to yield faster absorption of nicotine into the bloodstream than a similar solution containing distilled nicotine.

One notable contrast lies in the intensity brought about by increased nicotine concentrations. Freebase nicotine, with its elevated pH level, impacts alkalinity differently. Conversely, salt nicotine exhibits lower alkalinity, attributed to benzoic acid, resulting in a purportedly smoother throat hit, rendering vaping at 20 mg nicotine more tolerable.